EmeraNova™ ContactDistributor Portal

APIS®

Mānuka Honey Wound Solution

In partnership with Sweet Bio®, we offer a collagen derived dressing with a synthesis of proven materials: meticulously deconstructed natural elements to protect and cover wounds.

View Flyer
APIS® mānuka honey dressing

Known ingredients, powerful together

  • The pouch being opened
  • The sheet held in a gloved hand
  • The sheet on an open palm, for scale
  • APIS® dressing on a wound with an outer bandage partly covering it

Why clinicians choose it

  1. Backed by evidence. Published in multiple peer-reviewed publications demonstrating 4–8 week wound closure across both chronic and acute wounds.1–4*
  2. Engineered for use throughout the wound closure cascade. Supports wound closure across the early stages of bacteria and inflammation to the late stages of proliferation and remodeling.5–7*
  3. Next level convenience. Supplied in an all-in-one sheet, APIS® is ready to apply in minutes, can be trimmed or folded, and naturally conforms to the wound bed. APIS® resorbs as the wound progresses — no removal needed.
  4. Reimbursement-ready and operationally simple. APIS® billing pathway is available and ready to bill in this evolving reimbursement landscape. Established HCPCS code, A2010.

Sizes and SKUs

HCPCSA2010

SizeSKUBillable units**
1.6 x 1.6 cmAPIS®-16x16-23 cm²
2.5 x 2.5 cmAPIS®-25x25-26 cm²
4.0 x 4.0 cmAPIS®-40x40-216 cm²
5.0 x 5.0 cmAPIS®-50x50-225 cm²
6.0 x 8.0 cmAPIS®-60x80-248 cm²

* Based on clinical and in vitro data; claims have not been cleared by the FDA. Faster wound closure reported in slower healing and chronic wounds compared to standard of care.

** As of 2026, CMS no longer accepts wastage modifiers and providers are only to bill usage for the exact size of the wound.

References

1. Rodriguez et al. Novel bioengineered collagen + Manuka honey + hydroxyapatite sheet for the treatment of lower extremity chronic wounds in an urban hospital wound care setting. 2023.

2. Rodriguez et al. Preliminary clinical evaluation of a novel bioengineered wound product: A focus on the management of lower extremity ulcers. 2020.

3. McMurray et al. Use of a Novel Biomaterial to Enhance Secondary Intention Healing. 2021.

4. Arnaud et al. Novel Biomaterial Containing Gelatin, Manuka Honey, and Hydroxyapatite Enhanced Secondary Intention Healing Versus Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities — A Randomized Controlled Trial: Pilot Study. 2023.

5. Williams et al. A novel bioengineered wound product with in vitro capabilities to reduce bacteria. 2021.

6. Rodriguez et al. Microenvironment influence of a novel bioengineered wound product APIS®: An in vitro analysis of inflammatory marker and growth factor secretion. 2021.

7. Rodriguez et al. A Preliminary Direct Comparison of the Inflammatory Reduction and Growth Factor Production Capabilities of Three Commercially Available Wound Products: Collagen Sheet, Manuka Honey Sheet, and a Novel Bioengineered Collagen Derivative + Manuka Honey + Hydroxyapatite Sheet. 2022.

8. Dantas et al. 2011; Li et al. 2014; Pezeshki-Modaress et al. 2014; Pezeshki-Modaress et al. 2015.

9. Sell et al. 2012; Afrin et al. 2018; Johnston et al. 2018; Minden-Birkenmaier et al. 2018.

10. Okabayashi et al. 2009; Majeed et al. 2012; Kawai et al. 2011; Weilin et al. 2016; Tommila et al. 2008; Vilardell et al. 2016; Rodriguez et al. 2013 & 2016.