Synthetic Antimicrobial Matrix
Microlyte® PainGuard™ is a synthetic antimicrobial matrix containing ionic and metallic silver at low, non-toxic levels, providing a 99.99% reduction of a broad range of microbes on the matrix.1,2† The matrix also releases a uniform, unit-dose of lidocaine HCl, providing simultaneous pain relief.2
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Antimicrobial matrix with simultaneous pain relief
Why clinicians choose it
- Designed to assist in pain relief: >80% release of lidocaine HCl within the first 30 minutes.
- Synthetic, thin, porous matrix is made of resorbable polymers and designed to mimic human ECM.4,5
- Conforms with transparency to the micro-textures of the wound bed.

Sizes and SKUs
HCPCSA2040
| Size cm² | SKU | Wound coverage | Lidocaine per piece |
|---|---|---|---|
| 3x3 | I-MLPG0303 | 9cm² | 3.6 mg |
| 5x5 | I-MLPG0505 | 25cm² | 10 mg |
| 10x10 | I-MLPG1010 | 100cm² | 40 mg |
Other synthetics
References
1. Microlyte® Shelf Life and Stability. Data on file, Imbed Biosciences.
2. Measurement of Antimicrobial Activity of Microlyte® Ag. Data on file, Imbed Biosciences.
3. Agarwal A, et al. Surfaces modified with nanometer-thick silver-impregnated polymeric films that kill bacteria but support growth of mammalian cells. Biomaterials. 2010;31(4):680-90.
4. Product Handleability Evaluation Report. Data on file, Imbed Biosciences.
5. Systemic Toxicity, Local Tissue Response, and Wound Healing Study of Microlyte® Ag, Following Repeated Treatment to Full-Thickness Wounds in Rats — 28 Days. Data on file, Imbed Biosciences.
6. U.S. Food and Drug Administration. 510(k) Summary K211943: Microlyte® Ag/Lidocaine. FDA.gov. Published July 2021.
† As demonstrated in vitro








